| Goldstein
SM, Syed NA, Milam AH, Maguire AM, Lawton TJ, Nichols
CW.
Department of Ophthalmology, Scheie
Eye Institute and the Hospital of the University of Pennsylvania,
Philadelphia, USA.
Patients with systemic cancer may have a variety of ocular
complaints. Most commonly these are metastases or adverse
effects of therapy. Paraneoplastic syndromes, like cancer-associated
retinopathy, rarely cause ophthalmic symptoms. We describe
a patient with a malignant mixed mullerian tumor and cancer-associated
retinopathy who had circulating serum antibodies to recovering
and cells positive for recoverin in the tumor. We discuss
the typical clinical symptoms as well as the pathophysiology
of this uncommon disorder.
Arch Ophthalmol. 1999 Dec;117(12):1641-5.
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